What is the Epinephrine Injection, USP Auto-Injector?

Each Epinephrine Injection, USP Auto-Injector features numbered and color-coded instructions.

• Commercially insured patients may receive their epinephrine auto-injector at no cost. For more information, please see: here to view the Epinephrine Auto-Injector Savings Card.

What is the Impax Epinephrine Injection, USP Auto-Injector?

The Impax Epinephrine Injection, USP Auto-Injector is a disposable, prefilled automatic injection device (auto-injector) used to treat life-threatening, allergic emergencies (Type 1), including anaphylaxis, in people who are at risk for, or have a history of, serious allergic emergencies.

Epinephrine injection, USP auto-injector is intended for immediate administration as emergency therapy only and is not a replacement or substitute for immediate medical care. Talk with your healthcare provider about how to properly use the auto-injector. Training devices are available for practice by ordering here.

Each Impax Epinephrine Injector? features numbered and color-coded instructions.

*Commercially insured patients may receive their epinephrine auto-injector at $0 cost. Cash-paying patients may receive up to $25 off per pack out of their out-of-pocket cost. (Maximum benefit of $25 per pack.) For more information, please see here

IMPORTANT SAFETY INFORMATION

Epinephrine injection, USP auto-injector is intended for immediate administration as emergency supportive
therapy and is not intended as a substitute for immediate medical care. In conjunction with the administration of
epinephrine, the patient should seek immediate medical or hospital care. More than two sequential doses of
epinephrine should only be administered under direct medical supervision.

Epinephrine injection, USP auto-injector should ONLY be injected into the anterolateral aspect of the thigh. Do not
inject intravenously. Do not inject into buttock. Do not inject into fingers, hands or feet. Instruct caregivers to
hold the child’s leg firmly in place and limit movement prior to and during injection to minimize the risk of injection
related injury.

Epinephrine should be administered with caution to patients who have heart disease, including patients with
cardiac arrhythmias, coronary artery or organic heart disease, or hypertension. In such patients, or in patients who
are on drugs that may sensitize the heart to arrhythmias, epinephrine may precipitate or aggravate angina pectoris
as well as produce ventricular arrhythmias. Arrhythmias, including fatal ventricular fibrillation, have been reported
in patients with underlying cardiac disease or those receiving certain drugs. Patients who receive epinephrine
while concomitantly taking cardiac glycosides, diuretics or anti-arrhythmics should be observed carefully for the
development of cardiac arrhythmias. Epinephrine should be administered with caution to patients with
hyperthyroidism, diabetes, elderly individuals, and pregnant women. Patients with Parkinson’s disease may notice
a temporary worsening of symptoms.

Rare cases of serious skin and soft tissue infections, including necrotizing fasciitis and myonecrosis caused by
Clostridia, have been reported at the injection site following epinephrine injection for anaphylaxis. Advise patients
to seek medical care if they develop signs or symptoms of infection.