Anaphylaxis is a potentially life-threatening allergic reaction

When Anaphylaxis Phyl’s friends the “what-ifs” pop up, Epinephrine Injection, USP Auto-Injector* helps you be prepared for emergency treatment of severe allergic reaction (Type 1), including anaphylaxis—anywhere, anytime.

*authorized generic of Adrenaclick® (epinephrine injection, USP auto-injector).


There are many allergens, aka Anaphylaxis Phyl’s “what-if” friends, that can trigger a life-threatening allergic reaction (anaphylaxis), including food, stinging or biting insects, medication, and latex.

The Centers for Disease Control (CDC)* recommends administering epinephrine as a prompt treatment for these allergy emergencies.

*US Department of Health and Human Services, Centers for Disease Control and Prevention.

Why pay more for your Epinephrine Injection, USP Auto-Injector (Epinephrine Auto Injector)?

FDA-approved Epinephrine Injection, USP Auto-Injector (also called epinephrine auto-injector) is an affordable option for epinephrine.

Our auto-injector lets patients always be prepared with a convenient, easy-to-carry, single dose of epinephrine that they may give to themselves or may be given by a caregiver or healthcare provider.


Did you know that pharmacists can substitute a potentially more affordable option for the EpiPen® auto-injector? In all states, you or your pharmacist can request a prescription from your healthcare provider for the Epinephrine Auto-Injector.

Always be prepared for the “what-ifs”

Ask your doctor about a low-cost option, an Epinephrine Injection, USP Auto-Injector.†


Epinephrine injection, USP auto-injector is intended for immediate administration as emergency supportive
therapy and is not intended as a substitute for immediate medical care. In conjunction with the administration of
epinephrine, the patient should seek immediate medical or hospital care. More than two sequential doses of
epinephrine should only be administered under direct medical supervision.

Epinephrine injection, USP auto-injector should ONLY be injected into the anterolateral aspect of the thigh. Do not
inject intravenously. Do not inject into buttock. Do not inject into fingers, hands or feet. Instruct caregivers to
hold the child’s leg firmly in place and limit movement prior to and during injection to minimize the risk of injection
related injury.

Epinephrine should be administered with caution to patients who have heart disease, including patients with
cardiac arrhythmias, coronary artery or organic heart disease, or hypertension. In such patients, or in patients who
are on drugs that may sensitize the heart to arrhythmias, epinephrine may precipitate or aggravate angina pectoris
as well as produce ventricular arrhythmias. Arrhythmias, including fatal ventricular fibrillation, have been reported
in patients with underlying cardiac disease or those receiving certain drugs. Patients who receive epinephrine
while concomitantly taking cardiac glycosides, diuretics or anti-arrhythmics should be observed carefully for the
development of cardiac arrhythmias. Epinephrine should be administered with caution to patients with
hyperthyroidism, diabetes, elderly individuals, and pregnant women. Patients with Parkinson’s disease may notice
a temporary worsening of symptoms.

Rare cases of serious skin and soft tissue infections, including necrotizing fasciitis and myonecrosis caused by
Clostridia, have been reported at the injection site following epinephrine injection for anaphylaxis. Advise patients
to seek medical care if they develop signs or symptoms of infection.


What is the most important information I should know about epinephrine injection, USP auto-injector?

  1. Epinephrine injection, USP auto-injector contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen within minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise or other unknown causes. Symptoms of anaphylaxis may include:
    • trouble breathing
    • wheezing
    • hoarseness (changes in the way your voice sounds)
    • hives (raised reddened rash that may itch)
    • severe itching
    • swelling of your face, lips, mouth, or tongue
    • skin rash, redness, or swelling
    • fast heartbeat
    • weak pulse
    • feeling very anxious
    • confusion
    • stomach pain
    • losing control of urine or bowel movements (incontinence)
    • diarrhea or stomach cramps
    • dizziness, fainting, or “passing out” (unconsciousness).