Frequently Asked Questions


The epinephrine auto-injector is used to treat life-threatening allergic emergencies, including anaphylaxis in people who are at risk for, or have a history of serious allergic emergencies. Use of an epinephrine auto-injector must be followed by emergency medical care.

What are some of the allergic reactions that can cause anaphylaxis and require the use of an epinephrine auto-injector?
Allergic reactions can be caused by stinging and biting insects, allergy injections, food, medicines, exercise, or other unknown causes. These reactions, also called anaphylaxis or allergic emergencies, can be life-threatening and can happen within minutes.
What are some of the signs and symptoms of anaphylaxis?
Symptoms of anaphylaxis to be aware of include trouble breathing, wheezing, hoarseness (changes in the way your voice sounds), hives (raised reddened rash that may itch), severe itching, swelling of your face, lips, mouth, or tongue.*

*These are just some of the symptoms of anaphylaxis. Please check the Patient Information Leaflet or ask your healthcare provider for all of the symptoms.

If anaphylaxis is a risk, should my child keep an epinephrine auto-injector at school?
Yes, your child, as well as appropriate school personnel (such as a nurse), should have access to an epinephrine auto-injector while at school.
Does the epinephrine auto injector deliver the same medicine as other epinephrine auto-injectors?
Yes. All epinephrine auto-injectors use the same medicine, called epinephrine. It’s important to note that some devices may have unique features. It is essential that you become familiar with the features of your device so you are prepared in an emergency. Please consult your healthcare provider to become familiar with how to inject the epinephrine auto-injector.
Can I travel with my epinephrine auto-injector?
It’s recommended that you always keep your epinephrine auto-injector with you. If you will be traveling by plane, it’s suggested that you carry the epinephrine auto-injector in the original packaging and bring a letter from your physician that confirms your need to carry the auto-injector.
After I used my epinephrine auto-injector, I still see medicine remaining in my epinephrine auto-injector. Did I get my dose?
It is normal for some of the medicine to remain in the auto-injector after the dose is injected. The correct dose has been administered if you see the needle sticking out of the red tip. The remaining liquid that is left after this fixed dose cannot be further administered.
What should I do after I have received my dose?
The epinephrine auto-injector is for immediate self (or caregiver) administration and does not take the place of emergency medical care. You should get emergency medical help right away after using the epinephrine auto-injector.
Does my epinephrine auto-injector expire?
Yes, the epinephrine in the auto-injector does expire. You should check the expiration date often and obtain another auto-injector before it expires. You’ll find the expiration date in two places: on the label of the auto-injector itself and on the side panel of the package in which the auto-injector came in.
Can I reuse my epinephrine auto-injector?
No, the epinephrine auto-injector is designed for a one-time use only. It is important to use the epinephrine injection exactly as prescribed by your doctor or healthcare provider.
Why is the epinephrine auto-injector available in 2 dosage strengths?
The epinephrine auto-injector comes in two dose strengths because dosage is determined according to a person’s body weight. Your doctor will carefully determine which dose is right for you.
Are Trainer devices available for the epinephrine auto-injector?
Yes. Trainer devices are available and free. You may order Trainer devices two different ways; via our website OR you can call 1-855-374-6374 and order directly.


Epinephrine injection, USP auto-injector is intended for immediate administration as emergency supportive
therapy and is not intended as a substitute for immediate medical care. In conjunction with the administration of
epinephrine, the patient should seek immediate medical or hospital care. More than two sequential doses of
epinephrine should only be administered under direct medical supervision.

Epinephrine injection, USP auto-injector should ONLY be injected into the anterolateral aspect of the thigh. Do not
inject intravenously. Do not inject into buttock. Do not inject into fingers, hands or feet. Instruct caregivers to
hold the child’s leg firmly in place and limit movement prior to and during injection to minimize the risk of injection
related injury.

Epinephrine should be administered with caution to patients who have heart disease, including patients with
cardiac arrhythmias, coronary artery or organic heart disease, or hypertension. In such patients, or in patients who
are on drugs that may sensitize the heart to arrhythmias, epinephrine may precipitate or aggravate angina pectoris
as well as produce ventricular arrhythmias. Arrhythmias, including fatal ventricular fibrillation, have been reported
in patients with underlying cardiac disease or those receiving certain drugs. Patients who receive epinephrine
while concomitantly taking cardiac glycosides, diuretics or anti-arrhythmics should be observed carefully for the
development of cardiac arrhythmias. Epinephrine should be administered with caution to patients with
hyperthyroidism, diabetes, elderly individuals, and pregnant women. Patients with Parkinson’s disease may notice
a temporary worsening of symptoms.

Rare cases of serious skin and soft tissue infections, including necrotizing fasciitis and myonecrosis caused by
Clostridia, have been reported at the injection site following epinephrine injection for anaphylaxis. Advise patients
to seek medical care if they develop signs or symptoms of infection.


What is the most important information I should know about epinephrine injection, USP auto-injector?

  1. Epinephrine injection, USP auto-injector contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen within minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise or other unknown causes. Symptoms of anaphylaxis may include:
    • trouble breathing
    • wheezing
    • hoarseness (changes in the way your voice sounds)
    • hives (raised reddened rash that may itch)
    • severe itching
    • swelling of your face, lips, mouth, or tongue
    • skin rash, redness, or swelling
    • fast heartbeat
    • weak pulse
    • feeling very anxious
    • confusion
    • stomach pain
    • losing control of urine or bowel movements (incontinence)
    • diarrhea or stomach cramps
    • dizziness, fainting, or “passing out” (unconsciousness).