What are the Signs and Symptoms of Anaphylaxis?

What are the Signs and Symptoms of Anaphylaxis?

Signs and symptoms of anaphylaxis may begin within seconds or minutes of exposure to an allergen, but, in certain situations, symptoms may develop more than 30 minutes later.*

Symptoms of anaphylaxis may include

  • Trouble breathing
  • Wheezing
  • Hoarseness (changes in the way your voice sounds)
  • Hives (raised reddened rash that may itch)
  • Severe itching
  • Swelling of your face, lips, mouth, or tongue
  • Skin rash, redness, or swelling
  • Fast heartbeat
  • Weak pulse
  • Feeling very anxious
  • Confusion
  • Stomach pain
  • Losing control of urine or bowel movements (incontinence)
  • Diarrhea or stomach cramps
  • Dizziness, fainting, or “passing out” (unconsciousness)

*Source: Lieberman P, Nicklas R, Randolph C, et al. Anaphylaxis a practice parameter update 2015. Ann Allergy Asthma Immunol. 2015;115:341-384.

Signs and symptoms of anaphylaxis may begin within seconds or minutes of exposure to an allergen, but, in certain situations, symptoms may develop more than 30 minutes later.*

Symptoms of anaphylaxis may include

  • Trouble breathing
  • Wheezing
  • Hoarseness (changes in the way your voice sounds)
  • Hives (raised reddened rash that may itch)
  • Severe itching
  • Swelling of your face, lips, mouth, or tongue
  • Skin rash, redness, or swelling
  • Fast heartbeat
  • Weak pulse
  • Feeling very anxious
  • Confusion
  • Stomach pain
  • Losing control of urine or bowel movements (incontinence)
  • Diarrhea or stomach cramps
  • Dizziness, fainting, or “passing out” (unconsciousness)

*Source: Lieberman P, Nicklas R, Randolph C, et al. Anaphylaxis a practice parameter update 2015. Ann Allergy Asthma Immunol. 2015;115:341-384.

When you have an allergic emergency (anaphylaxis), begin treatment by using epinephrine auto-injector right away.

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Note

Epinephrine injection, USP auto-injector is for immediate self (or caregiver) administration and does not take the place of emergency medical care. You should get emergency medical help right away after using epinephrine injection, USP auto-injector.

Please see your healthcare provider for more information on anaphylaxis and potential triggers that may cause it.

Important Safety Information

What is the most important information I should know about epinephrine injection, USP auto-injector?


  1. Epinephrine injection, USP auto-injector contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen within minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise or other unknown causes. Symptoms of an anaphylaxis may include:
    • trouble breathing
    • wheezing
    • hoarseness (changes in the way your voice sounds)
    • hives (raised reddened rash that may itch)
    • severe itching
    • swelling of your face, lips, mouth, or tongue
    • skin rash, redness, or swelling
    • fast heartbeat
    • weak pulse
    • feeling very anxious
    • confusion
    • stomach pain
    • losing control of urine or bowel movements (incontinence)
    • diarrhea or stomach cramps
    • dizziness, fainting, or “passing out” (unconsciousness).
  2. Always carry your epinephrine injection, USP auto-injector with you because you may not know when anaphylaxis may happen. Talk to your healthcare provider if you need additional units to keep at work, school, or other locations. Tell your family members, caregivers, and others where you keep your epinephrine injection, USP auto-injector and how to use it before you need it. You may be unable to speak in an allergic emergency.
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