About Anaphylaxis

About Anaphylaxis

What is anaphylaxis?

Anaphylaxis is a potentially life-threatening allergic reaction that is rapid in onset and may cause severe swelling, breathing problems, loss of blood pressure, and death.*†‡§ Anaphylaxis can be caused by stinging and biting insects allergy injections, food, medicines, exercise, or other unknown causes.§

You should know…

Epinephrine, is the medicine of choice for someone experiencing an anaphylactic reaction.*§

Because anaphylaxis happens quickly, prompt recognition of the signs and symptoms of anaphylaxis is crucial.*

*Source: Lieberman P, Nicklas R, Randolph C, et al. Anaphylaxis a practice parameter update 2015. Ann Allergy Asthma Immunol. 2015;115:341-384.

Source: Sampson HA, Muñoz-Furlong A, Campbell RL, et al. Second symposium on the definition and management of anaphylaxis: summary report–Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network Symposium. J Allergy Clin Immunol. 2006;117(2):391-397.

Source: Simons FER. Anaphylaxis. J Allergy Clin Immunol. 2010;125(suppl 2):S161-S181.

§Source: Epinephrine injection, USP auto-injector. Patient Information Leaflet. Impax Laboratories, Inc. Hayward, CA: July 2016.

What is Anaphylaxis?

Anaphylaxis is a potentially life-threatening allergic reaction that is rapid in onset and may cause severe swelling, breathing problems, loss of blood pressure, and death.*§ Anaphylaxis can be caused by stinging and biting insects allergy injections, food, medicines, exercise, or other unknown causes.§

You should know…

Epinephrine, is the medicine of choice for someone experiencing an anaphylactic reaction.*†‡§

Because anaphylaxis happens quickly, prompt recognition of the signs and symptoms of anaphylaxis is crucial.*

*Source: Lieberman P, Nicklas R, Randolph C, et al. Anaphylaxis a practice parameter update 2015. Ann Allergy Asthma Immunol. 2015;115:341-384.

Source: Sampson HA, Muñoz-Furlong A, Campbell RL, et al. Second symposium on the definition and management of anaphylaxis: summary report–Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network Symposium. J Allergy Clin Immunol. 2006;117(2):391-397.

Source: Simons FER. Anaphylaxis. J Allergy Clin Immunol. 2010;125(suppl 2):S161-S181.

§Source: Epinephrine injection, USP auto-injector. Patient Information Leaflet. Impax Laboratories, Inc. Hayward, CA: July 2016.

Important Safety Information

What is the most important information I should know about epinephrine injection, USP auto-injector?


  1. Epinephrine injection, USP auto-injector contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen within minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise or other unknown causes. Symptoms of an anaphylaxis may include:
    • trouble breathing
    • wheezing
    • hoarseness (changes in the way your voice sounds)
    • hives (raised reddened rash that may itch)
    • severe itching
    • swelling of your face, lips, mouth, or tongue
    • skin rash, redness, or swelling
    • fast heartbeat
    • weak pulse
    • feeling very anxious
    • confusion
    • stomach pain
    • losing control of urine or bowel movements (incontinence)
    • diarrhea or stomach cramps
    • dizziness, fainting, or “passing out” (unconsciousness).
  2. Always carry your epinephrine injection, USP auto-injector with you because you may not know when anaphylaxis may happen. Talk to your healthcare provider if you need additional units to keep at work, school, or other locations. Tell your family members, caregivers, and others where you keep your epinephrine injection, USP auto-injector and how to use it before you need it. You may be unable to speak in an allergic emergency.
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