When to Use

Epinephrine injection, USP auto-injector, contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen within minutes, and can be caused by stinging and biting insects, allergy (immunotherapy) injections, foods, medicines, exercise, or other unknown causes.

Assess the situation. If you suspect you’re having a severe allergic reaction or are experiencing signs or symptoms of anaphylaxis, use the epinephrine injection, USP auto-injector, immediately. Epinephrine is the only first-line treatment for anaphylaxis. After an injection, seek emergency medical attention. You may need a second injection if symptoms continue or recur.

Only a healthcare professional should give additional doses of epinephrine should you need more than two for a single anaphylaxis episode.

Please note: symptoms of anaphylaxis can be mild and progress slowly or can appear rapidly with more severe symptoms.

The signs and symptoms of anaphylaxis may include:

  • Trouble breathing
  • Wheezing
  • Hoarseness (changes in the way your voice sounds)
  • Hives (raised, reddened rash that may itch)
  • Severe itching
  • Swelling of your face, lips, mouth, or tongue
  • Skin rash, redness, or swelling
  • Fast heartbeat
  • Weak pulse
  • Feeling very anxious
  • Confusion
  • Stomach pain
  • Losing control of urine or bowel movements (incontinence)
  • Diarrhea or stomach cramps
  • Dizziness, fainting, or “passing out” (unconsciousness)

When to Use

Epinephrine injection, USP auto-injector, contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen within minutes, and can be caused by stinging and biting insects, allergy (immunotherapy) injections, foods, medicines, exercise, or other unknown causes.

Assess the situation. If you suspect you’re having a severe allergic reaction or are experiencing signs or symptoms of anaphylaxis, use the epinephrine injection, USP auto-injector, immediately. Epinephrine is the only first-line treatment for anaphylaxis. After an injection, seek emergency medical attention. You may need a second injection if symptoms continue or recur.

Only a healthcare professional should give additional doses of epinephrine should you need more than two for a single anaphylaxis episode.

Please note: symptoms of anaphylaxis can be mild and progress slowly or can appear rapidly with more severe symptoms.

 

The signs and symptoms of anaphylaxis may include:

  • Trouble breathing
  • Wheezing
  • Hoarseness (changes in the way your voice sounds)
  • Hives (raised reddened rash that may itch)
  • Severe itching
  • Swelling of your face, lips, mouth, or tongue
  • Skin rash, redness, or swelling
  • Fast heartbeat
  • Weak pulse
  • Feeling very anxious
  • Confusion
  • Stomach pain
  • Losing control of urine or bowel movements (incontinence)
  • Diarrhea or stomach cramps
  • Dizziness, fainting, or “passing out” (unconsciousness)

Always be prepared for Anaphylaxis Phyl and the all-too-common “what-ifs”  that trigger him.

Epinephrine Injection, USP Auto-Injector, the generic Adrenaclick*®, gives you the ability to be prepared for and respond to a severe allergic reaction—anywhere, anytime

Always be prepared for the “what-ifs”.

Epinephrine Injection, USP Auto-Injector, the generic Adrenaclick®, gives you the ability to be prepared for and respond to a severe allergic reaction—anytime, anywhere.

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Epinephrine injection, USP auto-injector is for immediate self (or caregiver) administration and does not take the place of emergency medical care. You should get emergency medical help right away after using epinephrine injection, USP auto-injector.

Talk to your healthcare provider to find out more about anaphylaxis and potential triggers that may cause it.

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Please take a look at the American Academy of Allergy Asthma & Immunology Action Plan so you’re prepared in case of an anaphylactic reaction (www.aaaai.org).

IMPORTANT SAFETY INFORMATION

Epinephrine injection, USP auto-injector is intended for immediate administration as emergency supportive
therapy and is not intended as a substitute for immediate medical care. In conjunction with the administration of
epinephrine, the patient should seek immediate medical or hospital care. More than two sequential doses of
epinephrine should only be administered under direct medical supervision.

Epinephrine injection, USP auto-injector should ONLY be injected into the anterolateral aspect of the thigh. Do not
inject intravenously. Do not inject into buttock. Do not inject into fingers, hands or feet. Instruct caregivers to
hold the child’s leg firmly in place and limit movement prior to and during injection to minimize the risk of injection
related injury.

Epinephrine should be administered with caution to patients who have heart disease, including patients with
cardiac arrhythmias, coronary artery or organic heart disease, or hypertension. In such patients, or in patients who
are on drugs that may sensitize the heart to arrhythmias, epinephrine may precipitate or aggravate angina pectoris
as well as produce ventricular arrhythmias. Arrhythmias, including fatal ventricular fibrillation, have been reported
in patients with underlying cardiac disease or those receiving certain drugs. Patients who receive epinephrine
while concomitantly taking cardiac glycosides, diuretics or anti-arrhythmics should be observed carefully for the
development of cardiac arrhythmias. Epinephrine should be administered with caution to patients with
hyperthyroidism, diabetes, elderly individuals, and pregnant women. Patients with Parkinson’s disease may notice
a temporary worsening of symptoms.

Rare cases of serious skin and soft tissue infections, including necrotizing fasciitis and myonecrosis caused by
Clostridia, have been reported at the injection site following epinephrine injection for anaphylaxis. Advise patients
to seek medical care if they develop signs or symptoms of infection.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about epinephrine injection, USP auto-injector?

  1. Epinephrine injection, USP auto-injector contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen within minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise or other unknown causes. Symptoms of anaphylaxis may include:
    • trouble breathing
    • wheezing
    • hoarseness (changes in the way your voice sounds)
    • hives (raised reddened rash that may itch)
    • severe itching
    • swelling of your face, lips, mouth, or tongue
    • skin rash, redness, or swelling
    • fast heartbeat
    • weak pulse
    • feeling very anxious
    • confusion
    • stomach pain
    • losing control of urine or bowel movements (incontinence)
    • diarrhea or stomach cramps
    • dizziness, fainting, or “passing out” (unconsciousness).
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