Safety Information

Safety Information

Before you use epinephrine injection, USP auto-injector, tell your healthcare provider about all your medical conditions, especially if you:
  • Have heart problems or high blood pressure
  • Have diabetes
  • Have thyroid problems
  • Have asthma
  • Have a history of depression
  • Have Parkinson’s disease
  • Have any other medical conditions
  • Are pregnant or plan to become pregnant. It is not known if epinephrine will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if epinephrine passes into your breast milk
Epinephrine injection, USP auto-injector should only be injected into the middle of your outer thigh (upper leg). Do not inject epinephrine injection, USP auto-injector into your:
  • Veins
  • Buttocks
  • Fingers, toes, hands or feet
  • If you accidently inject epinephrine injection, USP auto-injector into any other part of you body, go to the nearest emergency room right away. Tell the healthcare provider where on your body you received the accidental injection.
Rarely, patients who use epinephrine injection, USP auto-injector may develop infections at the injection site within a few days of an injection. Some of these infections can be serious. Call your healthcare provider right away if you have any of the following at an injection site:
  • Redness that does not go away
  • Swelling
  • Tenderness
  • The area feels warm to the touch
Common side effects of epinephrine injection, USP auto-injector include:
  • Faster, irregular or “pounding” heartbeat
  • Sweating
  • Headache
  • Weakness
  • Shakiness
  • Paleness
  • Feelings of over excitement, nervousness, or anxiety
  • Dizziness
  • Nausea or vomiting
  • Breathing problems

These side effects may go away with rest. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of epinephrine injection, USP auto-injector. For more information, ask your healthcare provider or pharmacist.

Before you use epinephrine injection, USP auto-injector, tell your healthcare provider about all your medical conditions, especially if you:
  • Have heart problems or high blood pressure
  • Have diabetes
  • Have thyroid problems
  • Have asthma
  • Have a history of depression
  • Have Parkinson’s disease
  • Have any other medical conditions
  • Are pregnant or plan to become pregnant. It is not known if epinephrine will harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if epinephrine passes into your breast milk
Epinephrine injection, USP auto-injector should only be injected into the middle of your outer thigh (upper leg). Do not inject epinephrine injection, USP auto-injector into your:
  • Veins
  • Buttocks
  • Fingers, toes, hands or feet
  • If you accidently inject epinephrine injection, USP auto-injector into any other part of you body, go to the nearest emergency room right away. Tell the healthcare provider where on your body you received the accidental injection.
Rarely, patients who use epinephrine injection, USP auto-injector may develop infections at the injection site within a few days of an injection. Some of these infections can be serious. Call your healthcare provider right away if you have any of the following at an injection site:
  • Redness that does not go away
  • Swelling
  • Tenderness
  • The area feels warm to the touch
Common side effects of epinephrine injection, USP auto-injector include:
  • Faster, irregular or “pounding” heartbeat
  • Sweating
  • Headache
  • Weakness
  • Shakiness
  • Paleness
  • Feelings of over excitement, nervousness, or anxiety
  • Dizziness
  • Nausea or vomiting
  • Breathing problems

These side effects may go away with rest. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of epinephrine injection, USP auto-injector. For more information, ask your healthcare provider or pharmacist.

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Too much epinephrine can cause dangerously high blood pressure, stroke, or death.

If you have certain medical conditions, or take certain medicines, your condition may get worse or you may have more or longer lasting side effects when you use epinephrine injection, USP auto-injector. Talk to your healthcare provider about all your medical conditions.

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Important Safety Information

What is the most important information I should know about epinephrine injection, USP auto-injector?


  1. Epinephrine injection, USP auto-injector contains epinephrine, a medicine used to treat allergic emergencies (anaphylaxis). Anaphylaxis can be life-threatening, can happen within minutes, and can be caused by stinging and biting insects, allergy injections, foods, medicines, exercise or other unknown causes. Symptoms of an anaphylaxis may include:
    • trouble breathing
    • wheezing
    • hoarseness (changes in the way your voice sounds)
    • hives (raised reddened rash that may itch)
    • severe itching
    • swelling of your face, lips, mouth, or tongue
    • skin rash, redness, or swelling
    • fast heartbeat
    • weak pulse
    • feeling very anxious
    • confusion
    • stomach pain
    • losing control of urine or bowel movements (incontinence)
    • diarrhea or stomach cramps
    • dizziness, fainting, or “passing out” (unconsciousness).
  2. Always carry your epinephrine injection, USP auto-injector with you because you may not know when anaphylaxis may happen. Talk to your healthcare provider if you need additional units to keep at work, school, or other locations. Tell your family members, caregivers, and others where you keep your epinephrine injection, USP auto-injector and how to use it before you need it. You may be unable to speak in an allergic emergency.
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